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DeCS
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Descriptor English:
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Histocompatibility Antigens Class I
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Descriptor Spanish:
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Antígenos de Histocompatibilidad Clase I
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Descriptor Portuguese:
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Antígenos de Histocompatibilidade Classe I
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Synonyms English:
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Class I Histocompatibility Antigens
Class I Human Antigens
Class I Major Histocompatibility Antigens
Human Class I Antigens
Antigens, Class I
I Antigens, Class
Class I Antigens
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Tree Number:
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D12.776.395.550.489
D12.776.543.550.439
D23.050.301.500.100
D23.050.705.552.100
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Definition English:
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Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells. |
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Indexing Annotation English:
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human & animal
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History Note English:
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89
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Allowable Qualifiers English:
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Record Number:
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23664
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Unique Identifier:
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D015395
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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